Sarcoid-like granulomatosis in patients treated with anti-TNFα factors. A case report and review of the literature
Identifieur interne : 001669 ( Main/Exploration ); précédent : 001668; suivant : 001670Sarcoid-like granulomatosis in patients treated with anti-TNFα factors. A case report and review of the literature
Auteurs : Theoni Kanellopoulou [Grèce] ; Anna Filiotou [Grèce] ; Hariklia Kranidioti [Grèce] ; Spyridon P. Dourakis [Grèce]Source :
- Clinical Rheumatology [ 0770-3198 ] ; 2011-04-01.
English descriptors
- KwdEn :
Abstract
Abstract: This report describes a 56-year-old woman who developed granulomatous lesions consistent with sarcoidosis during adalimumab therapy for rheumatoid arthritis. Cervical and axillary lymphadenopathy developed approximately 21 months after adalimumab administration. Non-caseating epithelioid cell granulomas consistent with sarcoidosis were detected both in an axillary lymph node specimen and in the bone marrow. Diseases showing similar histologic changes, especially tuberculosis, were excluded, and a diagnosis of sarcoidosis was made. Adalimumab was discontinued, and recovery was observed. The current case is, to our knowledge, the first to describe adalimumab-induced non-caseating granulomas in lymph nodes and bone marrow without pulmonary involvement in a patient treated for rheumatoid arthritis.
Url:
DOI: 10.1007/s10067-010-1603-3
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001696
- to stream Istex, to step Curation: 001696
- to stream Istex, to step Checkpoint: 000614
- to stream Main, to step Merge: 001672
- to stream Main, to step Curation: 001669
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Sarcoid-like granulomatosis in patients treated with anti-TNFα factors. A case report and review of the literature</title><author><name sortKey="Kanellopoulou, Theoni" sort="Kanellopoulou, Theoni" uniqKey="Kanellopoulou T" first="Theoni" last="Kanellopoulou">Theoni Kanellopoulou</name></author><author><name sortKey="Filiotou, Anna" sort="Filiotou, Anna" uniqKey="Filiotou A" first="Anna" last="Filiotou">Anna Filiotou</name></author><author><name sortKey="Kranidioti, Hariklia" sort="Kranidioti, Hariklia" uniqKey="Kranidioti H" first="Hariklia" last="Kranidioti">Hariklia Kranidioti</name></author><author><name sortKey="Dourakis, Spyridon P" sort="Dourakis, Spyridon P" uniqKey="Dourakis S" first="Spyridon P." last="Dourakis">Spyridon P. Dourakis</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:6360AAFBEAB44ECD26676D83DD98B0B90E9C7091</idno><date when="2010" year="2010">2010</date><idno type="doi">10.1007/s10067-010-1603-3</idno><idno type="url">https://api.istex.fr/ark:/67375/VQC-6BMC9KHX-R/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">001696</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001696</idno><idno type="wicri:Area/Istex/Curation">001696</idno><idno type="wicri:Area/Istex/Checkpoint">000614</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000614</idno><idno type="wicri:doubleKey">0770-3198:2010:Kanellopoulou T:sarcoid:like:granulomatosis</idno><idno type="wicri:Area/Main/Merge">001672</idno><idno type="wicri:Area/Main/Curation">001669</idno><idno type="wicri:Area/Main/Exploration">001669</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Sarcoid-like granulomatosis in patients treated with anti-TNFα factors. A case report and review of the literature</title><author><name sortKey="Kanellopoulou, Theoni" sort="Kanellopoulou, Theoni" uniqKey="Kanellopoulou T" first="Theoni" last="Kanellopoulou">Theoni Kanellopoulou</name><affiliation wicri:level="3"><country xml:lang="fr">Grèce</country><wicri:regionArea>2nd Department of Internal Medicine, Medical School of Athens University, “Hippokration” General Hospital of Athens, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Grèce</country><wicri:regionArea>48, Satovriandou str. 124-62, Haidari</wicri:regionArea><wicri:noRegion>Haidari</wicri:noRegion></affiliation><affiliation></affiliation></author><author><name sortKey="Filiotou, Anna" sort="Filiotou, Anna" uniqKey="Filiotou A" first="Anna" last="Filiotou">Anna Filiotou</name><affiliation wicri:level="3"><country xml:lang="fr">Grèce</country><wicri:regionArea>2nd Department of Internal Medicine, Medical School of Athens University, “Hippokration” General Hospital of Athens, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Kranidioti, Hariklia" sort="Kranidioti, Hariklia" uniqKey="Kranidioti H" first="Hariklia" last="Kranidioti">Hariklia Kranidioti</name><affiliation wicri:level="3"><country xml:lang="fr">Grèce</country><wicri:regionArea>2nd Department of Internal Medicine, Medical School of Athens University, “Hippokration” General Hospital of Athens, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Dourakis, Spyridon P" sort="Dourakis, Spyridon P" uniqKey="Dourakis S" first="Spyridon P." last="Dourakis">Spyridon P. Dourakis</name><affiliation wicri:level="3"><country xml:lang="fr">Grèce</country><wicri:regionArea>2nd Department of Internal Medicine, Medical School of Athens University, “Hippokration” General Hospital of Athens, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Clinical Rheumatology</title><title level="j" type="sub">Journal of the International League of Associations for Rheumatology</title><title level="j" type="abbrev">Clin Rheumatol</title><idno type="ISSN">0770-3198</idno><idno type="eISSN">1434-9949</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>London</pubPlace><date type="published" when="2011-04-01">2011-04-01</date><biblScope unit="volume">30</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="581">581</biblScope><biblScope unit="page" to="583">583</biblScope></imprint><idno type="ISSN">0770-3198</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0770-3198</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adalimumab</term><term>Anti-TNF</term><term>Rheumatoid arthritis</term><term>Sarcoidosis</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: This report describes a 56-year-old woman who developed granulomatous lesions consistent with sarcoidosis during adalimumab therapy for rheumatoid arthritis. Cervical and axillary lymphadenopathy developed approximately 21 months after adalimumab administration. Non-caseating epithelioid cell granulomas consistent with sarcoidosis were detected both in an axillary lymph node specimen and in the bone marrow. Diseases showing similar histologic changes, especially tuberculosis, were excluded, and a diagnosis of sarcoidosis was made. Adalimumab was discontinued, and recovery was observed. The current case is, to our knowledge, the first to describe adalimumab-induced non-caseating granulomas in lymph nodes and bone marrow without pulmonary involvement in a patient treated for rheumatoid arthritis.</div></front></TEI><affiliations><list><country><li>Grèce</li></country><region><li>Attique (région)</li></region><settlement><li>Athènes</li></settlement></list><tree><country name="Grèce"><region name="Attique (région)"><name sortKey="Kanellopoulou, Theoni" sort="Kanellopoulou, Theoni" uniqKey="Kanellopoulou T" first="Theoni" last="Kanellopoulou">Theoni Kanellopoulou</name></region><name sortKey="Dourakis, Spyridon P" sort="Dourakis, Spyridon P" uniqKey="Dourakis S" first="Spyridon P." last="Dourakis">Spyridon P. Dourakis</name><name sortKey="Filiotou, Anna" sort="Filiotou, Anna" uniqKey="Filiotou A" first="Anna" last="Filiotou">Anna Filiotou</name><name sortKey="Kanellopoulou, Theoni" sort="Kanellopoulou, Theoni" uniqKey="Kanellopoulou T" first="Theoni" last="Kanellopoulou">Theoni Kanellopoulou</name><name sortKey="Kranidioti, Hariklia" sort="Kranidioti, Hariklia" uniqKey="Kranidioti H" first="Hariklia" last="Kranidioti">Hariklia Kranidioti</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001669 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001669 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= ChloroquineV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:6360AAFBEAB44ECD26676D83DD98B0B90E9C7091
|texte= Sarcoid-like granulomatosis in patients treated with anti-TNFα factors. A case report and review of the literature
}}
| This area was generated with Dilib version V0.6.33. |  |